DYRK1A Inhibitors as Potential Therapeutics for β-Cell Regeneration for Diabetes-Reference-Cited by-同舟云学术

DYRK1A Inhibitors as Potential Therapeutics for β-Cell Regeneration for Diabetes

Published:2021-03-08 Issue:6 Volume:64 Page:2901-2922
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Kumar Kunal¹,Suebsuwong Chalada¹,Wang Peng²,Garcia-Ocana Adolfo²,Stewart Andrew F.²,DeVita Robert J.¹^ORCID

Affiliation:

1. Drug Discovery Institute and Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York 10029, United States

2. Diabetes, Obesity, and Metabolism Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, United States

Funder

National Institute of Diabetes and Digestive and Kidney Diseases

JDRF

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.0c02050

Reference103 articles.

1. Executive Summary Global Reports on Diabetes; World Health Organization, 2014.

2. National Diabetes Satistics Report; Center for Disease Control and Prevention (CDC), 2020.

3. Genetics, pathogenesis and clinical interventions in type 1 diabetes

4. The Stunned β Cell: A Brief History

5. Sustained beta cell apoptosis in patients with long-standing type 1 diabetes: indirect evidence for islet regeneration?

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