Lipophilicity in Drug Development: Too Much or Not Enough?
Author:
Publisher
Springer Science and Business Media LLC
Subject
Pharmaceutical Science
Link
http://link.springer.com/content/pdf/10.1208/s12248-016-9947-5.pdf
Reference16 articles.
1. Lipinski CA, Lombardo F, Dominy BW, Feeny PJ. Experimental and computational approaches to estimate solubility and permeabilty in drug discovery and development settings. Adv Drug Deliv Rev. 1997;23:3–25.
2. Jain N, Yalkowsky SH. Estimation of the aqueous solubility I: application to organic nonelectrolytes. J Pharm Sci. 2001;90(2):234–52.
3. Wassvik CM, Holmen AG, Draheim R, Artursson P, Bergström CAS. Molecular characteristics for solid-state limited solubility. J Med Chem. 2008;51(10):3035–9.
4. Bergström CAS, Charman WN, Porter CJ. Computational prediction of formulation strategies for beyond-rule-of-5 compounds. Adv Drug Deliv Rev. 2016;101:6–21.
5. Leeson PD. Molecular inflation, attrition and the rule of five. Adv Drug Deliv Rev. 2016;101:22–33.
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