Molecular Characteristics for Solid-State Limited Solubility-Reference-Cited by-同舟云学术

Molecular Characteristics for Solid-State Limited Solubility

Published:2008-04-09 Issue:10 Volume:51 Page:3035-3039
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Wassvik Carola M.¹,Holmén Anders G.¹,Draheim Rieke¹,Artursson Per¹,Bergström Christel A. S.¹

Affiliation:

1. Pharmaceutical Screening and Informatics, Department of Pharmacy, Uppsala University, Uppsala Biomedical Centre, Post Office Box 580, SE-75123 Uppsala, Sweden, and Lead Generation, AstraZeneca R&D Mölndal, SE-43183 Mölndal, Sweden

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm701587d

Reference21 articles.

1. Drug-like properties and the causes of poor solubility and poor permeability

2. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

3. Formulation of poorly water-soluble drugs for oral administration: Physicochemical and physiological issues and the lipid formulation classification system

4. Poorly Soluble Marketed Drugs Display Solvation Limited Solubility

5. Estimation of the aqueous solubility I: Application to organic nonelectrolytes

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