Novel-Type GABA<sub>B</sub> PAMs: Structure–Activity Relationship in Light of the Protein Structure-Reference-Cited by-同舟云学术

Novel-Type GABA_B PAMs: Structure–Activity Relationship in Light of the Protein Structure

Published:2024-03-01 Issue:3 Volume:15 Page:396-405
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Krámos Balázs¹^ORCID,Hadady Zsuzsa²,Makó Attila²,Szántó Gábor²,Felföldi Nóra²,Magdó Ildikó¹,Bobok Amrita Ágnes³,Bata Imre²,Román Viktor³,Visegrády András³,Keserű György M.⁴,Greiner István⁵^ORCID,Éles János⁶^ORCID

Affiliation:

1. Spectroscopic Research Department, Gedeon Richter Plc., Gyömrői út 19-21, Budapest, 1103 Hungary

2. Chemistry Department, Gedeon Richter Plc., Gyömrői út 19-21, Budapest, 1103 Hungary

3. Pharmacological and Drug Safety Research, Gedeon Richter Plc., Gyömrői út 19-21, Budapest, 1103 Hungary

4. Medicinal Chemistry Research Group, Research Centre for Natural Sciences, Magyar tudósok krt. 2, Budapest, 1117 Hungary

5. Research and Development Director, Gedeon Richter Plc., Gyömrői út 19-21, Budapest, 1103 Hungary

6. Head of Medicinal Chemistry, Gedeon Richter Plc., Gyömrői út 19-21, Budapest, 1103 Hungary

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.3c00560

Reference29 articles.

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4. GABAB receptors: synaptic functions and mechanisms of diversity

5. Altered response to benzodiazepine anxiolytics in mice lacking GABAB(1) receptors