Molecular inflation, attrition and the rule of five

Author:

Leeson Paul D.

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference111 articles.

1. Improving drug candidates by design: a focus on physicochemical properties as a means of improving compound disposition and safety;Meanwell;Chem. Res. Toxicol.,2011

2. Physicochemical properties and compound quality;Gleeson,2015

3. Physical properties in drug design;Young;Topics Med. Chem.,2015

4. Probing the links between in vitro potency, ADMET and physicochemical parameters;Gleeson;Nat. Rev. Drug Discov.,2011

5. Toxicology strategies for drug discovery: present and future;Blomme;Chem. Res. Toxicol.,2015

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