Comparison of Fraction Unbound Between Liver Homogenate and Hepatocytes at 4°C
Author:
Publisher
Springer Science and Business Media LLC
Subject
Pharmaceutical Science
Link
https://link.springer.com/content/pdf/10.1208/s12248-020-00476-7.pdf
Reference29 articles.
1. Billington S, Nguyen TB, Kumar V, Ishida K, Unadkat JD, Billington S, et al. Positron emission tomography imaging of [(11) C]Rosuvastatin hepatic concentrations and hepatobiliary transport in humans in the absence and presence of Cyclosporin A. Clin Pharmacol Ther. 2019;106(5):1056–66.
2. K-i K, Tanaka M, Ishii A, Katayama Y, Nakaoka T, Irie S, et al. A clinical quantitative evaluation of hepatobiliary transport of [11C] dehydropravastatin in humans using positron emission tomography. Drug Metab Dispos. 2018;46(5):719–28. https://doi.org/10.1124/dmd.118.080408.
3. Li R, Kimoto E, Niosi M, Tess DA, Lin J, Tremaine LM, et al. A study on pharmacokinetics of bosentan with systems modeling, part 2: prospectively predicting systemic and liver exposure in healthy subjects. Drug Metab Dispos. 2018;46(4):357–66, S1-S14. https://doi.org/10.1124/dmd.117.078808.
4. Riccardi K, Lin J, Li Z, Niosi M, Ryu S, Hua W, et al. Novel method to predict in vivo liver-to-plasma Kpuu for OATP substrates using suspension hepatocytes. Drug Metab Dispos. 2017;45(5):576–80. https://doi.org/10.1124/dmd.116.074575.
5. Morse BL, Cai H, MacGuire JG, Fox M, Zhang L, Zhang Y, et al. Rosuvastatin liver partitioning in cynomolgus monkeys: measurement in vivo and prediction using in vitro monkey hepatocyte uptake. Drug Metab Dispos. 2015;43(11):1788–94. https://doi.org/10.1124/dmd.115.065946.
Cited by 11 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Successful Prediction of Human Hepatic Concentrations of Transported Drugs Using the Proteomics‐Informed Relative Expression Factor Approach;Clinical Pharmacology & Therapeutics;2023-12-18
2. Comparison of Tumor Binding Across Tumor Types and Cell Lines to Support Free Drug Considerations for Oncology Drug Discovery;Journal of Pharmaceutical Sciences;2023-11
3. Transplacental passage of hyperforin, hypericin, and valerenic acid;Frontiers in Pharmacology;2023-03-31
4. Non-specific binding of compounds in in vitro metabolism assays: a comparison of microsomal and hepatocyte binding in different species and an assessment of the accuracy of prediction models;Xenobiotica;2022-08-03
5. Placental Passage of Protopine in an Ex Vivo Human Perfusion System;Planta Medica;2022-04-20
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3