Predictions of In Vivo Prolactin Levels from In Vitro K i Values of D2 Receptor Antagonists Using an Agonist–Antagonist Interaction Model-Reference-Cited by-同舟云学术

Predictions of In Vivo Prolactin Levels from In Vitro K i Values of D2 Receptor Antagonists Using an Agonist–Antagonist Interaction Model

Published:2013-02-08 Issue:2 Volume:15 Page:533-541
ISSN:1550-7416
Container-title:The AAPS Journal
language:en
Short-container-title:AAPS J

Author:

Petersson Klas J.,Vermeulen An M.,Friberg Lena E.

Publisher

Springer Science and Business Media LLC

Subject

Pharmaceutical Science

Link

http://link.springer.com/content/pdf/10.1208/s12248-012-9450-6.pdf

Reference33 articles.

1. Kapur S, Remington G. Dopamine D(2) receptors and their role in atypical antipsychotic action: still necessary and may even be sufficient. Biol Psychiatry. 2001;50(11):873–83.

2. Biedermann F, Fleischhacker WW. Emerging drugs for schizophrenia. Expert Opin Emerg Drugs. 2011;16(2):271–82.

3. Petty RG. Prolactin and antipsychotic medications: mechanism of action. Schizophr Res. 1999;35(Suppl):S67–73.

4. Turrone P, Kapur S, Seeman MV, Flint AJ. Elevation of prolactin levels by atypical antipsychotics. Am J Psychiatry. 2002;159(1):133–5.

5. Meltzer HY, Matsubara S, Lee JC. Classification of typical and atypical antipsychotic drugs on the basis of dopamine D-1, D-2 and serotonin2 pKi values. J Pharmacol Exp Ther. 1989;251(1):238–46.

Cited by 5 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Fingerprints of CNS drug effects: a plasma neuroendocrine reflection of D2 receptor activation using multi-biomarker pharmacokinetic/pharmacodynamic modelling;British Journal of Pharmacology;2018-08-31

2. Modeling of prolactin response following dopamine D2 receptor antagonists in rats: can it be translated to clinical dosing?;Pharmacology Research & Perspectives;2017-11-21

3. A comparison of two semi-mechanistic models for prolactin release and prediction of receptor occupancy following administration of dopamine D 2 receptor antagonists in rats;European Journal of Pharmacology;2016-10

4. Reversibility of dopamine receptor antagonist-induced hyperprolactinemia and associated histological changes in Tg RasH2 wild-type mice;Reproductive Toxicology;2015-12

5. Clozapine, a Fast-Off-D2 Antipsychotic;ACS Chemical Neuroscience;2013-11-18