Fingerprints of CNS drug effects: a plasma neuroendocrine reflection of D2 receptor activation using multi-biomarker pharmacokinetic/pharmacodynamic modelling
Author:
Affiliation:
1. Division of Systems Biomedicine and Pharmacology, Leiden Academic Center for Drug Research; Leiden University; Leiden The Netherlands
2. Certara QSP, Canterbury Innovation House; Canterbury UK
Publisher
Wiley
Subject
Pharmacology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/bph.14452/fullpdf
Reference53 articles.
1. Prefrontal, accumbal [shell] and ventral striatal mechanisms in jaw movements and non-cyclase-coupled dopamine D1-like receptors;Adachi;Eur J Pharmacol,2003
2. The Concise Guide to PHARMACOLOGY 2017/18: G protein-coupled receptors;Alexander;Br J Pharmacol,2017
3. Dopamine infusion acutely inhibits the TSH and prolactin response to TRH;Besses;J Endocrinol Metab,1975
4. Operational models of pharmacological agonism;Black;Proc R Soc B Biol Sci,1983
5. D1 and D2 dopamine receptors stimulate hypothalamo-pituitary-adrenal activity in rats;Borowsky;Neuropharmacology,1992
Cited by 6 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Approaches Towards Prediction of CNS PK and PD;Drug Delivery to the Brain;2022
2. Targeting for Success: Demonstrating Proof-of-Concept with Mechanistic Early Phase Clinical Pharmacology Studies for Disease-Modification in Neurodegenerative Disorders;International Journal of Molecular Sciences;2021-02-05
3. Systems Pharmacology: Enabling Multidimensional Therapeutics;Reference Module in Biomedical Sciences;2021
4. Drug repurposing in neurological diseases: an integrated approach to reduce trial and error;Journal of Neurology, Neurosurgery & Psychiatry;2019-06-06
5. Physiologically Based Modeling Approach to Predict Dopamine D2 Receptor Occupancy of Antipsychotics in Brain: Translation From Rat to Human;The Journal of Clinical Pharmacology;2019-01-24
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3