Pulmonary Infections in the Elderly Lead to Impaired Neutrophil Targeting, Which Is Improved by Simvastatin-Reference-Cited by-同舟云学术

Pulmonary Infections in the Elderly Lead to Impaired Neutrophil Targeting, Which Is Improved by Simvastatin

Published:2017-11-15 Issue:10 Volume:196 Page:1325-1336
ISSN:1073-449X
Container-title:American Journal of Respiratory and Critical Care Medicine
language:en
Short-container-title:Am J Respir Crit Care Med

Author:

Sapey Elizabeth¹^ORCID,Patel Jaimin M.¹,Greenwood Hannah L.¹,Walton Georgia M.¹,Hazeldine Jon¹,Sadhra Charendeep¹,Parekh Dhruv¹,Dancer Rachel C. A.¹,Nightingale Peter²,Lord Janet M.¹,Thickett David R.¹

Affiliation:

1. Institute of Inflammation and Ageing, University of Birmingham, Edgbaston, United Kingdom; and

2. Medical Statistics, University Hospital Birmingham NHS Foundation Trust, Birmingham, United Kingdom

Publisher

American Thoracic Society

Subject

Critical Care and Intensive Care Medicine,Pulmonary and Respiratory Medicine

Link

http://www.atsjournals.org/doi/pdf/10.1164/rccm.201704-0814OC

Reference47 articles.

1. Association of Diagnostic Coding With Trends in Hospitalizations and Mortality of Patients With Pneumonia, 2003-2009

2. Ageing and infection

3. Phosphoinositide 3-kinase inhibition restores neutrophil accuracy in the elderly: toward targeted treatments for immunosenescence

4. Impaired neutrophil extracellular trap formation: a novel defect in the innate immune system of aged individuals

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