Peptide nucleic acids targeted to the neurotensin receptor and administered i.p. cross the blood-brain barrier and specifically reduce gene expression-Reference-Cited by-同舟云学术

Peptide nucleic acids targeted to the neurotensin receptor and administered i.p. cross the blood-brain barrier and specifically reduce gene expression

Published:1999-06-08 Issue:12 Volume:96 Page:7053-7058
ISSN:0027-8424
Container-title:Proceedings of the National Academy of Sciences
language:en
Short-container-title:Proceedings of the National Academy of Sciences

Author:

Tyler B. M.,Jansen K.,McCormick D. J.,Douglas C. L.,Boules M.,Stewart J. A.,Zhao L.,Lacy B.,Cusack B.,Fauq A.,Richelson E.

Publisher

Proceedings of the National Academy of Sciences

Subject

Multidisciplinary

Reference27 articles.

1. Stability of peptide nucleic acids in human serum and cellular extracts

2. Antisense and Antigene Properties of Peptide Nucleic Acids

3. Mechanism of Lac repressor switch-off: orientation of the Lac repressor DNA-binding domain is reversed upon inducer binding

Cited by 120 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Preclinical Pharmacokinetics in Tumors and Normal Tissues of the Antigene PNA Oligonucleotide MYCN-Inhibitor BGA002;Nucleic Acid Therapeutics;2024-08-01

2. Novel systemic delivery of a peptide-conjugated antisense oligonucleotide to reduce α-synuclein in a mouse model of Alzheimer's disease;Neurobiology of Disease;2023-10

3. Explorations into Peptide Nucleic Acid Contrast Agents as Emerging Scaffolds for Breakthrough Solutions in Medical Imaging and Diagnosis;ACS Omega;2021-10-19

4. Pharmacodynamic and pharmacokinetic profiles of a neurotensin receptor type 2 (NTS2) analgesic macrocyclic analog;Biomedicine & Pharmacotherapy;2021-09

5. Cholesterol-functionalized DNA/RNA heteroduplexes cross the blood–brain barrier and knock down genes in the rodent CNS;Nature Biotechnology;2021-08-12