Modelling Species Selectivity in Rat and Human Cytochrome P450 2D Enzymes
Author:
Publisher
Public Library of Science (PLoS)
Subject
Multidisciplinary
Reference26 articles.
1. Homology modeling of rat and human cytochrome P450 2D (CYP2D) isoforms and computational rationalization of experimental ligand-binding specificities;J Venhorst;Journal of Medicinal Chemistry,2003
2. Quantitative structure-activity relationships (QSARs) for inhibitors and substrates of CYP2B enzymes: importance of compound lipophilicity in explanation of potency differences;DFV Lewis;Journal of Enzyme Inhibition and Medicinal Chemistry,2010
3. Classification Models for Predicting Cytochrome P450 Enzyme-Substrate Selectivity;T Zhang;Molecular Informatics,2012
4. QM/MM Modeling of Benzene Hydroxylation in Human Cytochrome P450 2C9;CM Bathelt;Journal of Physical Chemistry A,2008
5. Antibody-antigen Interactions: Contact Analysis and Binding Site Topography;RM MacCallum;Journal of Molecular Biology,1996
Cited by 10 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Bioactivation and reactivity research advances – 2022 year in review‡;Drug Metabolism Reviews;2023-08-22
2. A comparative review of the activity of enzymes of the cytochrome P450 system in humans and laboratory animals. Prognostic value of preclinical models in vivo;Translational Medicine;2022-12-28
3. Bioavailability and Pharmacokinetics of Endoxifen in Female Rats and Dogs: Evidence to Support the Use of Endoxifen to Overcome the Limitations of CYP2D6-Mediated Tamoxifen Metabolism;Drug Metabolism and Disposition;2022-11-09
4. Metabolism of the lipophilic phycotoxin 13-Desmethylspirolide C using human and rat in vitro liver models;Toxicology Letters;2019-06
5. Toward Computational Understanding of Molecular Recognition in the Human Metabolizing Cytochrome P450s;Current Medicinal Chemistry;2018-09-04
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3