Detection of SARS-CoV-2 lineage P.1 in patients from a region with exponentially increasing hospitalisation rate, February 2021, Rio Grande do Sul, Southern Brazil-Reference-Cited by-同舟云学术

Detection of SARS-CoV-2 lineage P.1 in patients from a region with exponentially increasing hospitalisation rate, February 2021, Rio Grande do Sul, Southern Brazil

Published:2021-03-25 Issue:12 Volume:26 Page:
ISSN:1560-7917
Container-title:Eurosurveillance
language:en
Short-container-title:

Author:

Martins Andreza Francisco¹²³⁴^ORCID,Zavascki Alexandre Prehn³⁵²⁶^ORCID,Wink Priscila Lamb⁷⁴³^ORCID,Volpato Fabiana Caroline Zempulski⁸⁷³^ORCID,Monteiro Francielle Liz⁷³^ORCID,Rosset Clévia⁹⁷^ORCID,De-Paris Fernanda⁷³^ORCID,Ramos Álvaro Krüger¹⁰^ORCID,Barth Afonso Luís³⁴⁷⁸^ORCID

Affiliation:

1. Bioinformatic Core, Hospital de Clínicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil

2. These authors contributed equally to the work as first authors.

3. LABRESIS – Laboratório de Pesquisa em Resistência Bacteriana, Hospital de Clínicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil

4. Programa de Pós-Graduação em Ciências Farmacêuticas, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil

5. Internal Medicine Department, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil

6. Infectious Diseases Service, Hospital de Clínicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil

7. Laboratório de Diagnóstico de SARS-CoV-2, Hospital de Clínicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil

8. Programa de Pós-Graduação em Ciências Médicas, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil

9. Laboratório de Medicina Genômica (LMG), Hospital de Clínicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil

10. Programa de Pós-Graduação em Matemática, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil

Abstract

The emergence of SARS-CoV-2 P.1 lineage coincided with a surge in hospitalisations in the North region of Brazil. In the South region’s Rio Grande do Sul state, severe COVID-19 case numbers rose 3.8 fold in February 2021. During that month, at a COVID-19 referral hospital in this state, whole-genome sequencing of a subset of cases’ specimens (n = 27) revealed P.1 lineage SARS-CoV-2 in most (n = 24). Findings raise concerns regarding a possible association between lineage P.1 and rapid case and hospitalisation increases.

Publisher

European Centre for Disease Control and Prevention (ECDC)

Subject

Virology,Public Health, Environmental and Occupational Health,Epidemiology

Reference13 articles.

1. Secretaria da Saúde do Estado do Rio Grande do Sul. Painel Coronavírus RS. Portuguese. [Accessed 6 Mar 2021]. Available from: https://ti.saude.rs.gov.br/covid19

2. Centers for Disease Control and Prevention, Respiratory Viruses Branch, Division of Viral Diseases. Real-time RT-PCR panel for detection 2019-novel coronavirus. Atlanta: CDC; 2020. [Accessed 27 Jul 2020]. Available from: https://www.fda.gov/media/134922/download

3. Pangolin: lineage assignment in an emerging pandemic as an epidemiological tool. [Accessed 28 Feb 2021]. Available from: http://pangolin.cog-uk.io/

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