Effect of Fresh vs Standard-issue Red Blood Cell Transfusions on Multiple Organ Dysfunction Syndrome in Critically Ill Pediatric Patients

Author:

Spinella Philip C.1,Tucci Marisa2,Fergusson Dean A.3,Lacroix Jacques2,Hébert Paul C.4,Leteurtre Stéphane5,Schechtman Kenneth B.6,Doctor Allan1,Berg Robert A.7,Bockelmann Tina1,Caro J. Jaime89,Chiusolo Fabrizio10,Clayton Lucy11,Cholette Jill M.12,Guerra Gonzalo Garcia1314,Josephson Cassandra D.1516,Menon Kusum17,Muszynski Jennifer A.18,Nellis Marianne E.19,Sarpal Amrita20,Schafer Stephanie1,Steiner Marie E.21,Turgeon Alexis F.22,

Affiliation:

1. Division of Critical Care, Department of Pediatrics, Washington University School of Medicine in St Louis, St Louis, Missouri

2. Division of Pediatric Critical Care, Centre Hospitalier Universitaire (CHU) Sainte-Justine, Université de Montréal and Centre de Recherche du Centre Hospitalier de l’Université de Montréal, Montreal, Quebec, Canada

3. Ottawa Hospital Research Institute, Departments of Medicine & Surgery, University of Ottawa School of Epidemiology and Public Health, University of Ottawa, Ottawa, Ontario, Canada

4. Département de médecine, Centre de recherche du CHUM and Chaire de médecine transfusionnelle Héma-Québec-Bayer de l'Université de Montréal, Centre hospitalier de l'Université de Montréal, Montreal, Quebec, Canada

5. Université de Lille, EA 2694—Santé publique: épidémiologie et qualité des soins, CHU Lille, Réanimation Pédiatrique, Lille, France

6. Division of Biostatistics, Washington University School of Medicine in St Louis, St Louis, Missouri

7. The Children’s Hospital of Philadelphia, Anesthesiology and Critical Care, University of Pennsylvania, Philadelphia

8. London School of Economics, London, United Kingdom

9. Evidera, Boston, Massachusetts

10. Department of Anesthesia and Critical Care, Bambino Gesù Children’s Hospital, Rome, Italy

11. Division of Pediatric Critical, Department of Pediatrics, Centre Hospitalier Universitaire (CHU) Sainte-Justine Université de Montréal and Centre de Recherche du Centre Hospitalier de l’Université de Montréal, Montreal, Quebec, Canada

12. Division of Critical Care and Cardiology, Department of Pediatrics, University of Rochester Golisano Children’s Hospital, Rochester, New York

13. Department of Pediatrics, University of Alberta, Edmonton, Canada

14. Stollery Children’s Hospital, Edmonton, Alberta, Canada

15. Departments of Pathology and Pediatrics, Emory University School of Medicine, Atlanta, Georgia

16. Transfusion, Tissue, Apheresis Services, Children’s Healthcare of Atlanta, Atlanta, Georgia

17. Children’s Hospital of Eastern Ontario, University of Ottawa, Ottawa, Canada

18. Division of Critical Care Medicine, Department of Pediatrics, Nationwide Children’s Hospital, Columbus, Ohio

19. Division of Pediatric Critical Care, Department of Pediatrics, Weill Cornell Medicine, New York, New York

20. Western University, Children's Hospital, London Health Sciences Centre, London, Ontario, Canada

21. Division of Pediatric Hematology and Oncology, Division of Pediatric Critical Care Medicine, Department of Pediatrics, University of Minnesota Medical School, Minneapolis

22. Research CHU de Québec—Université Laval Centre, Population Health and Optimal Health Practices and Research Unit, Trauma, Emergency, Critical Care Medicine, Université Laval and Department of Anesthesiology and Critical Care Medicine, Division of Critical Care Medicine, Faculty of Medicine, Université Laval, Québec City, Québec, Canada

Publisher

American Medical Association (AMA)

Subject

General Medicine

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