1. From the Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL (CMS, JS, ARD, MLD, and LVH); the Department of Epidemiology and Biostatistics, School of Public Health (IJB, QC, and PE), and the Medical Research Council–Health Protection Agency Centre for Environment and Health (PE), Imperial College London, St Mary's Campus, London, United Kingdom; t