Abstract
Antimicrobial resistance is growing worldwide and presents risks such as a pandemic. It is caused by the overuse or misdirected use of antibiotics. Regulation of antibiotic use can be accompanied by herbal drugs such as turmeric, pepper, & clover, etc., that have been found to be effective for millennia with no emergence of resistance reported, due to their polyphenols and alkaloids or combination, also emerging as “superfoods” due to their inclusion in the regular diet. Combined herbal therapy may be synergistic, preventing the evolution of resistance among the microbes. The cultivation of such superfoods can double farmers' income due to the growing demand and low input costs and save threatened wild herbs from extinction.
Reference37 articles.
1. Ghate U and Kulkarni H. Polyphenols, Spices and Vegetarian Diet for Immunity and Anti-Inflammatory Drug Design. in Zepka L Q et al (eds.) Bioactive Compounds - Biosynthesis, Characterization and Applications, Intech, 2021, London.
2. Wilson D W, P Nash, H S Buttar, K Griffiths, R Singh, F D M R Horiuchi and T Takahashi,. The Role of Food Antioxidants, Benefits of Functional Foods, and Influence of Feeding Habits on the Health of the Older Person: An Overview. Antioxidants (Basel). 2017 Dec; 6(4): 81.
3. Ventola CL. The antibiotic resistance crisis: part 1: causes and threats. P T. 2015
4. WHO, Antimicrobial resistance. World health Organisation, 2023 Geneva. https://www.who.int/news-room/fact-sheets/detail/antimicrobial-resistance
5. Aggarwal B at al, Identification of Novel Anti-inflammatory Agents from Ayurvedic Medicine for Prevention of Chronic Diseases- “Reverse Pharmacology” and “Bedside to Bench” Approach. Curr Drug Targets. 2011 Oct 1; 12(11): 1595–1653.