Determination of free light chains: assay-dependent differences in interpretation-Reference-Cited by-同舟云学术

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Determination of free light chains: assay-dependent differences in interpretation

Published:2020-09-02 Issue:2 Volume:59 Page:e69-e71
ISSN:1437-4331
Container-title:Clinical Chemistry and Laboratory Medicine (CCLM)
language:en
Short-container-title:

Author:

Bossuyt Xavier¹²,Poesen Koen³⁴,Sprangers Ben⁵,Reynders Martin³,Vercammen Martine⁶,Delforge Michel⁷

Affiliation:

1. Department of Microbiology, Immunology and Transplantation , Clinical and Diagnostic Immunology , KU Leuven, Leuven , Belgium

2. Department of Laboratory Medicine , University Hospitals Leuven , Leuven , Belgium

3. Laboratory Medicine , Immunology, University Hospitals Leuven , Leuven , Belgium

4. Department of Neurosciences, Laboratory for molecular neurobiomarker research , KU Leuven , Leuven , Belgium

5. Nephrology, University Hospitals Leuven , Leuven , Belgium

6. Department of Laboratory Medicine , AZ Sint-Jan , Brugge , Belgium

7. Hematology, University Hospitals Leuven , Leuven , Belgium

Publisher

Walter de Gruyter GmbH

Subject

Biochemistry, medical,Clinical Biochemistry,General Medicine

Link

https://www.degruyter.com/document/doi/10.1515/cclm-2020-0938/pdf

Reference10 articles.

1. Katzmann, JA, Clark, RJ, Abraham, RS, Bryant, S, Lymp, JF, Bradwell, AR, et al. Serum reference intervals and diagnostic ranges for free kappa and free lambda immunoglobulin light chains: relative sensitivity for detection of monoclonal light chains. Clin Chem 2002;48:1437–44. https://doi.org/10.1093/clinchem/48.9.1437.

2. te Velthuis, H, Knop, I, Stam, P, van den Broek, M, Bos, HK, Hol, S, et al. N Latex FLC - new monoclonal high-performance assays for the determination of free light chain kappa and lambda. Clin Chem Lab Med 2011;49:1323–32. https://doi.org/10.1515/cclm.2011.624.

3. Cotten, SW, Shajani-Yi, Z, Cervinski, MA, Voorhees, T, Tuchman, SA, Korpi-Steiner, N. Reference intervals and diagnostic ranges for serum free κ and free λ immunoglobulin light chains vary by instrument platform: implications for classification of patient results in a multi-center study. Clin Biochem 2018;58:100–7. https://doi.org/10.1016/j.clinbiochem.2018.06.003.

4. Bossuyt, X, Delforge, M, Reynders, M, Dillaerts, D, Sprangers, B, Fostier, K, et al. Diagnostic thresholds for free light chains in multiple myeloma depend on the assay used. Leukemia 2018;32:1815–18. https://doi.org/10.1038/s41375-018-0041-0.

5. Jacobs, JF, Hoedemakers, RM, Teunissen, E, Te Velthuis, H. N Latex FLC serum free light-chain assays in patients with renal impairment. Clin Chem Lab Med 2014;52:853–9. https://doi.org/10.1515/cclm-2013-0864.

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1. An updated diagnostic range for serum free light chain kappa/lambda ratio using Freelite reagents on BN II or Optilite;Pathology;2024-08

2. Inter-assay diagnostic accuracy of cerebrospinal fluid kappa free light chains for the diagnosis of multiple sclerosis;Frontiers in Immunology;2024-04-30

3. In response to: Defining new reference intervals for serum free light chains in individuals with chronic kidney disease: results of the iStopMM study;Blood Cancer Journal;2022-11-14

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