New lupan-type triterpenoids-Reference-Cited by-同舟云学术

New lupan-type triterpenoids

Published:2016-09-14 Issue:11-12 Volume:71 Page:381-386
ISSN:1865-7125
Container-title:Zeitschrift für Naturforschung C
language:en
Short-container-title:

Author:

Mkounga Pierre¹,Maza Hermine L.D.²,Ouahouo Blandine M.W.²,Tyon Lydie N.²,Ishikawa Hayato³,Nishino Hiroshi³,Nkengfack Augustin E.²

Affiliation:

1. Department of Organic Chemistry, University of Yaounde I, Faculty of Science, PO Box 812 Yaounde, Cameroon , Fax: +237 222 23 44 96

2. Department of Organic Chemistry, University of Yaounde I, Faculty of Science, PO Box 812 Yaounde, Cameroon

3. Department of Chemistry Graduate School of Science and Technology, Kumamoto University, Kurokami 2-39-1, Chûou-ku, Kumamoto 860-8555, Japan

Abstract

Abstract Three new lupan-type triterpernoid derivatives, namely globimetulin A (1), B (2) and C (3), were isolated from the shoot of Globimetula dinklagei (Loranthaceae), a hemiparasitic plant growing on Manihot esculenta, along with five known compounds: friedelin (4), friedelan-3-ol (5), 28-hydroxyfriedelin (6), 4-hydroxy-3,5-dimethoxybenzoic acid (7) and (1R,5S,7S)-7-[2-(4-hydroxyphenyl)ethyl]-2,6-dioxabicyclo[3.3.1]nonan-3-one (8). The structures of the new compounds were elucidated by detailed analyses of their MS, IR, 1D and 2D NMR spectral data and chemical evidence. Some of these compounds were evaluated in vitro for their antimicrobial activities against a wide range of microorganisms, but none of them exhibited noticeable activity.

Publisher

Walter de Gruyter GmbH

Subject

General Biochemistry, Genetics and Molecular Biology

Link

https://www.degruyter.com/document/doi/10.1515/znc-2015-0235/pdf

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