Microbial Enantioselective Ester Hydrolysis for the Preparation of Optically Active 4,1-Benzoxazepine-3-acetic Acid Derivatives as Squalene Synthase Inhibitors.-Reference-Cited by-同舟云学术

Microbial Enantioselective Ester Hydrolysis for the Preparation of Optically Active 4,1-Benzoxazepine-3-acetic Acid Derivatives as Squalene Synthase Inhibitors.

Published:2002 Issue:1 Volume:50 Page:59-65
ISSN:0009-2363
Container-title:Chemical and Pharmaceutical Bulletin
language:en
Short-container-title:CHEMICAL & PHARMACEUTICAL BULLETIN

Author:

Tarui Naoki¹,Nakahama Kazuo¹,Nagano Yoichi¹,Izawa Motowo¹,Matsumoto Kiyoharu¹,Kori Masakuni¹,Nagata Toshiaki²,Miki Takashi¹,Yukimasa Hidefumi¹

Affiliation:

1. Takeda Chemical Industries, Ltd., Pharmaceutical Research Division

2. Takeda Chemical Industries, Ltd., Pharmaceutical Production Division

Publisher

Pharmaceutical Society of Japan

Subject

Drug Discovery,General Chemistry,General Medicine

Link

http://www.jstage.jst.go.jp/article/cpb/50/1/50_1_59/_pdf

Reference15 articles.

1. Syntheses of (4,1-Benzoxazepine-3-ylidene)acetic Acid Derivatives and Their Inhibition of Squalene Synthase.

2. The biocatalytic approach to the preparation of enantiomerically pure chiral building blocks

3. 3) Sakamoto K., Tsuzaki K., Shima M., JP 09308497 (1997), [Chem. Abstr., 128, 74400 (1997)].

4. 4) Ozaki E., Uragaki T., JP 09059217 (1997), [Chem. Abstr., 126, 277200 (1997)].

5. 5) Ozaki E., Uragaki T., JP 09059211 (1997), [Chem. Abstr., 126, 277199 (1997)].

Cited by 6 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Process Research on the Asymmetric Hydrogenation of a Benzophenone for Developing the Manufacturing Process of the Squalene Synthase Inhibitor TAK-475;Organic Process Research & Development;2011-08-26

2. ChemInform Abstract: 4,1-Benzoxazepine Derivatives as Squalene Synthase Inhibitors. Part 4. Microbial Enantioselective Ester Hydrolysis for the Preparation of Optically Active 4,1-Benzoxazepine-3-acetic Acid Derivatives as Squalene Synthase Inhibitors.;ChemInform;2010-05-20

3. Synthesis and Chemical Transformations of Benzoxazepines;HETEROCYCLES;2008

4. Synthesis and biological evaluation of novel propylamine derivatives as orally active squalene synthase inhibitors;Bioorganic & Medicinal Chemistry;2004-11

5. Syntheses and biological evaluation of novel quinuclidine derivatives as squalene synthase inhibitors;Bioorganic & Medicinal Chemistry;2003-05-29