Pim kinase inhibitors: a survey of the patent literature
Author:
Publisher
Informa Healthcare
Subject
Drug Discovery,Pharmacology,General Medicine
Link
http://www.tandfonline.com/doi/pdf/10.1517/13543770903496442
Reference68 articles.
1. The serine/threonine kinase Pim-2 is a transcriptionally regulated apoptotic inhibitor
2. The pim-1 oncogene encodes two related protein-serine/threonine kinases by alternative initiation at AUG and CUG.
3. Murine leukemia virus-induced T-cell lymphomagenesis: Integration of proviruses in a distinct chromosomal region
4. Proviral tagging in E mu-myc transgenic mice lacking the Pim-1 proto-oncogene leads to compensatory activation of Pim-2.
5. Proto-oncogene, Pim-3 with serine/threonine kinase activity, is aberrantly expressed in human colon cancer cells and can prevent Bad-mediated apoptosis
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1. A review on structure-function mechanism and signaling pathway of serine/threonine protein PIM kinases as a therapeutic target;International Journal of Biological Macromolecules;2024-06
2. Imparting aromaticity to 2-pyridone derivatives by O -alkylation resulted in new competitive and non-competitive PIM-1 kinase inhibitors with caspase-activated apoptosis;Journal of Enzyme Inhibition and Medicinal Chemistry;2024-01-17
3. Biological evaluation of carbazoyl hydrazine derivatives as potential Pim-1 kinase inhibitors for the treatment of human liver cancer;Journal of Molecular Structure;2024-01
4. Discovery of new pyridine-quinoline hybrids as competitive and non-competitive PIM-1 kinase inhibitors with apoptosis induction and caspase 3/7 activation capabilities;Journal of Enzyme Inhibition and Medicinal Chemistry;2023-01-11
5. Therapeutic targeting of PIM KINASE signaling in cancer therapy: Structural and clinical prospects;Biochimica et Biophysica Acta (BBA) - General Subjects;2021-11
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