Design, Synthesis, Anticancer Evaluation and Molecular Docking Studies of Amide Derivatives of Thienopyrimidine Isoxazoles-Reference-Cited by-同舟云学术

Design, Synthesis, Anticancer Evaluation and Molecular Docking Studies of Amide Derivatives of Thienopyrimidine Isoxazoles

Published:2024-03-13 Issue:5 Volume:56 Page:439-450
ISSN:0030-4948
Container-title:Organic Preparations and Procedures International
language:en
Short-container-title:Organic Preparations and Procedures International

Author:

Ramesh Babu Vankayala¹,Rangaswamy Singamsetty¹,Lakshmi SVVNSM²,Musuluri Murali³,Mak Kit-Kay⁴⁵,Syed Tasqeeruddin⁶,Lakshmi Bavisetti¹,Abbaraju V.D.N. Kumar⁷

Affiliation:

1. Department of Chemistry, GITAM School of Science, Gandhi Institute of Technology and Management (Deemed to be University), Visakhapatnam, India

2. Department of Pharmacognosy, Vishnu Institute of Pharmaceutical Education & Research, Narsapur, India

3. Department of Chemistry, RVR & JC College of Engineering, Chowdavaram, Guntur, India

4. Pharmaceutical Chemistry Department, School of Pharmacy, International Medical University, Kuala Lumpur, Malaysia

5. Centre of Excellence for Bioactive Molecules and Drug Delivery, Institute for Research, Development, and Innovation (IRDI), International Medical University, Kuala Lumpur, Malaysia

6. Department of Pharmaceutical Chemistry, College of Pharmacy, King Khalid University, Abha, Saudi Arabia

7. Department of Environmental Science, GITAM School of Science, Gandhi Institute of Technology and Management (Deemed to be University), Visakhapatnam, India

Publisher

Informa UK Limited

Link

https://www.tandfonline.com/doi/pdf/10.1080/00304948.2024.2316449

Reference30 articles.

1. Synthesis and biological evaluation of 2,6-disubstituted-9H-purine, 2,4-disubstitued-thieno[3,2-d]pyrimidine and -7H-pyrrolo[2,3-d]pyrimidine analogues as novel CHK1 inhibitors

2. 3D Pharmacophore Model-Assisted Discovery of Novel CDC7 Inhibitors

3. Identification and SAR of a new series of thieno[3,2-d]pyrimidines as Tpl2 kinase inhibitors

4. Identification of GNE-477, a potent and efficacious dual PI3K/mTOR inhibitor

5. Discovery of a Potent, Selective, and Orally Available Class I Phosphatidylinositol 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Kinase Inhibitor (GDC-0980) for the Treatment of Cancer

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