Identification and SAR of a new series of thieno[3,2-d]pyrimidines as Tpl2 kinase inhibitors-Reference-Cited by-同舟云学术

Identification and SAR of a new series of thieno[3,2-d]pyrimidines as Tpl2 kinase inhibitors

Published:2011-10 Issue:19 Volume:21 Page:5952-5956
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Ni Yike,Gopalsamy Ariamala,Cole Derek,Hu Yonghan,Denny Rajiah,Ipek Manus,Liu Julie,Lee Julie,Hall J. Perry,Luong Michael,Telliez Jean-Baptiste,Lin Lih-Ling

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference18 articles.

1. The Tpl2 MutationSluggishImpairs Type I IFN Production and Increases Susceptibility to Group B Streptococcal Disease

2. Cot/Tpl-2 Protein Kinase as a Target for the Treatment of Inflammatory Disease

3. Pharmacologic Inhibition of Tpl2 Blocks Inflammatory Responses in Primary Human Monocytes, Synoviocytes, and Blood

4. Cytokine Pathways and Joint Inflammation in Rheumatoid Arthritis

5. Anti-TNFα Therapy of Rheumatoid Arthritis: What Have We Learned?

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