The VEGF-A exon 8 splicing-sensitive fluorescent reporter mouse is a novel tool to assess the effects of splicing regulatory compounds in vivo-Reference-Cited by-同舟云学术

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The VEGF-A exon 8 splicing-sensitive fluorescent reporter mouse is a novel tool to assess the effects of splicing regulatory compounds in vivo

Published:2019-08-21 Issue:12 Volume:16 Page:1672-1681
ISSN:1547-6286
Container-title:RNA Biology
language:en
Short-container-title:RNA Biology

Author:

Stevens M.¹,Star E.²,Lee M.²,Innes E.¹,Li L.¹,Bowler E.¹,Harper S.¹³,Bates D. O.⁴,Oltean S.¹

Affiliation:

1. Institute of Biomedical and Clinical Science, Medical School, College of Medicine and Health, University of Exeter, Exeter, UK

2. Bristol Renal, School of Clinical Sciences, University of Bristol, Bristol, UK

3. School of Physiology, Pharmacology & Neuroscience, University of Bristol, Bristol, UK

4. Cancer Biology, Division of Cancer and Stem Cells, School of Medicine, University of Nottingham, Nottingham, UK

Publisher

Informa UK Limited

Subject

Cell Biology,Molecular Biology

Link

https://www.tandfonline.com/doi/pdf/10.1080/15476286.2019.1652522

Reference33 articles.

1. Alternative splicing: increasing diversity in the proteomic world

2. New prospects in the roles of the C-terminal domains of VEGF-A and their cooperation for ligand binding, cellular signaling and vessels formation

3. Vascular Endothelial Growth Factor (VEGF)-A165b Is a WeakIn vitroAgonist for VEGF Receptor-2 Due to Lack of Coreceptor Binding and Deficient Regulation of Kinase Activity

4. Topical Antiangiogenic SRPK1 Inhibitors Reduce Choroidal Neovascularization in Rodent Models of Exudative AMD

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1. RNA splicing based on reporter genes system: Detection, imaging and applications;Coordination Chemistry Reviews;2023-02

2. Identification of novel somatic fusions of ERG‐VEGFA, TMPRSS2‐ERG , and VEGFA‐TMPRSS2 in prostate cancer treated with anlotinib and androgen deprivation therapy: A case report;Cancer Innovation;2022-06

3. Management of age-related macular degeneration;Age-Related Macular Degeneration;2022

4. VEGF gene polymorphisms regulate human retinal vascular endothelial cell proliferation and apoptosis through ASF/SF2-associated alternative splicing;European Journal of Ophthalmology;2021-11-26

5. A drug-repositioning screen using splicing-sensitive fluorescent reporters identifies novel modulators of VEGF-A splicing with anti-angiogenic properties;Oncogenesis;2021-05

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