Regioselective approach to colchiceine tropolone ring functionalization at C(9) and C(10) yielding new anticancer hybrid derivatives containing heterocyclic structural motifs-Reference-Cited by-同舟云学术

Regioselective approach to colchiceine tropolone ring functionalization at C(9) and C(10) yielding new anticancer hybrid derivatives containing heterocyclic structural motifs

Published:2022-01-24 Issue:1 Volume:37 Page:597-605
ISSN:1475-6366
Container-title:Journal of Enzyme Inhibition and Medicinal Chemistry
language:en
Short-container-title:Journal of Enzyme Inhibition and Medicinal Chemistry

Author:

Pyta Krystian¹,Skrzypczak Natalia¹,Ruszkowski Piotr²,Bartl Franz³,Przybylski Piotr¹^ORCID

Affiliation:

1. Faculty of Chemistry, Adam Mickiewicz University, Poznan, Poland

2. Department of Pharmacology, Poznan University of Medical Sciences, Poznan, Poland

3. Lebenswissenschaftliche Fakultät, Institut für Biologie, Biophysikalische Chemie Humboldt-Universität zu Berlin Invalidenstraße 42, Berlin, Germany

Funder

Polish National Science Centre

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/14756366.2022.2028782

Reference55 articles.

1. Colchicine as an anti-inflammatory and cardioprotective agent

2. Colchicine: an ancient drug with novel applications

3. Conformation of tropolone ring in antileukemic tropoloisoquinoline alkaloids.