Biocatalytic route to C-4′-spiro-oxetano-xylofuranosyl pyrimidine nucleosides
Author:
Affiliation:
1. Department of Chemistry, Bioorganic Laboratory, University of Delhi, Delhi, India
Funder
University of Delhi
Publisher
Informa UK Limited
Subject
Biochemistry,Catalysis,Biotechnology
Link
https://www.tandfonline.com/doi/pdf/10.1080/10242422.2018.1438416
Reference32 articles.
1. 3'-Spiro nucleosides, a new class of specific human immunodeficiency virus type 1 inhibitors: synthesis and antiviral activity of [2', 5'-bis-O-(tert-butyldimethylsilyl)-.beta.-D-xylo- and -ribofuranose]-3'-spiro-5''-[4''-amino-1'', 2''-oxathiole 2'', 2''-dioxide] (TSAO) pyrimidine nucleosides
2. Syntheses of 4′-spirocyclic phosphono-nucleosides as potential inhibitors of hepatitis C virus NS5B polymerase
3. Syntheses of nucleosides with 2′-spirolactam and 2′-spiropyrrolidine moieties as potential inhibitors of hepatitis C virus NS5B polymerase
4. Crystal Structure of tert-Butyldimethylsilyl-spiroaminooxathioledioxide-thymine (TSAO-T) in Complex with HIV-1 Reverse Transcriptase (RT) Redefines the Elastic Limits of the Non-nucleoside Inhibitor-Binding Pocket
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