Delayed Effects in the Exposure-Response Analysis of Clinical QTc Trials
Author:
Affiliation:
1. a Clinical Biostatistics , Boehringer Ingelheim Pharma GmbH & Co. KG , Biberach , Germany
Publisher
Informa UK Limited
Subject
Pharmacology (medical),Pharmacology,Statistics and Probability
Link
https://www.tandfonline.com/doi/pdf/10.1080/10543406.2010.539309
Reference6 articles.
1. Commentary on the Clinical Relevance of Concentration/QTc Relationships for New Drug Candidates
2. Concentration-QT Relationships Play a Key Role in the Evaluation of Proarrhythmic Risk During Regulatory Review
3. Thorough QT Study with Recommended and Supratherapeutic Doses of Tolterodine
4. A Perspective on the Use of Concentration-QT Modeling in Drug Development
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