Hypermethylation of PI3K-AKT signalling pathway genes is associated with human neural tube defects

Author:

Tian Tian12,Lai Xinyuan3,Xiang Kuanhui3,Han Xiao4,Yin Shengju5,Cabrera Robert M.4,Steele John W.4,Lei Yunping4,Cao Xuanye4,Finnell Richard H.46,Wang Linlin12ORCID,Ren Aiguo12ORCID

Affiliation:

1. Institute of Reproductive and Child Health, National Health Commission Key Laboratory of Reproductive Health, Peking University, Beijing, China

2. Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing, China

3. Department of Microbiology and Infectious Disease Center, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China

4. Center for Precision Environmental Health, Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA

5. Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, China

6. Departments of Molecular and Human Genetics and Medicine, Baylor College of Medicine, Houston, TX, USA

Funder

This work was supported

Ministry of Science and Technology of the People’s Republic of China

National Institutes of Health

Publisher

Informa UK Limited

Subject

Cancer Research,Molecular Biology

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