T cell repertoire to citrullinated self-peptides in healthy humans is not confined to the HLA-DR SE alleles; Targeting of citrullinated self-peptides presented by HLA-DP4 for tumour therapy-Reference-Cited by-同舟云学术

T cell repertoire to citrullinated self-peptides in healthy humans is not confined to the HLA-DR SE alleles; Targeting of citrullinated self-peptides presented by HLA-DP4 for tumour therapy

Published:2019-02-20 Issue:5 Volume:8 Page:e1576490
ISSN:2162-402X
Container-title:OncoImmunology
language:en
Short-container-title:OncoImmunology

Author:

Brentville Victoria A¹,Symonds Peter¹,Cook Katherine W¹^ORCID,Daniels Ian¹^ORCID,Pitt Tracy¹,Gijon Mohamed¹^ORCID,Vaghela Poonam¹,Xue Wei¹,Shah Sabaria¹,Metheringham Rachael L¹,Durrant Lindy G¹²

Affiliation:

1. Scancell Limited, Academic Department of Clinical Oncology, University of Nottingham, City Hospital Campus, Nottingham, UK

2. Academic Department of Clinical Oncology, Division of Cancer and Stem Cells, School of Medicine, University of Nottingham, City Hospital Campus, Nottingham, UK

Funder

Scancell Ltd

Publisher

Informa UK Limited

Subject

Oncology,Immunology,Immunology and Allergy

Link

https://tandfonline.com/doi/pdf/10.1080/2162402X.2019.1576490

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1. Demonstration of extracellular peptidylarginine deiminase (PAD) activity in synovial fluid of patients with rheumatoid arthritis using a novel assay for citrullination of fibrinogen

2. Expression and activity of citrullinating peptidylarginine deiminase enzymes in monocytes and macrophages

3. Citrulline-Specific Th1 Cells Are Increased in Rheumatoid Arthritis and Their Frequency Is Influenced by Disease Duration and Therapy