Citrulline-Specific Th1 Cells Are Increased in Rheumatoid Arthritis and Their Frequency Is Influenced by Disease Duration and Therapy

Author:

James Eddie A.1,Rieck Mary1,Pieper Jennifer2,Gebe John A.1,Yue Betty B.1,Tatum Megan1,Peda Melissa1,Sandin Charlotta2,Klareskog Lars2,Malmström Vivianne2,Buckner Jane H.1

Affiliation:

1. Benaroya Research Institute at Virginia Mason; Seattle Washington

2. Karolinska Institutet; Stockholm Sweden

Funder

National Institute of Allergy and Infectious Diseases

National Institute of Arthritis and Musculoskeletal and Skin Diseases

Boehringer Ingelheim Fonds

European Research Council

EU FP7 project Masterswitch

IMI JU funded project BTCure

King Gustaf V 80 year Foundation

Margaretha af Ugglas Foundation

Swedish Association against Rheumatism

Swedish Medical Association

Swedish Research Council

Publisher

Wiley

Subject

Immunology,Rheumatology,Immunology and Allergy

Reference41 articles.

1. Rheumatoid arthritis;Klareskog;Lancet,2009

2. The pathogenesis of rheumatoid arthritis;McInnes;N Engl J Med,2011

3. Rheumatoid factors antedating clinical rheumatoid arthritis;Aho;J Rheumatol,1991

4. Antikeratin antibody and antiperinuclear factor as markers for subclinical rheumatoid disease process;Aho;J Rheumatol,1993

5. Citrulline is an essential constituent of antigenic determinants recognized by rheumatoid arthritis-specific autoantibodies;Schellekens;J Clin Invest,1998

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