Identification of novel inhibitor of protein tyrosine phosphatases delta: structure-based pharmacophore modeling, virtual screening, flexible docking, molecular dynamics simulation, and post-molecular dynamics analysis-Reference-Cited by-同舟云学术

Identification of novel inhibitor of protein tyrosine phosphatases delta: structure-based pharmacophore modeling, virtual screening, flexible docking, molecular dynamics simulation, and post-molecular dynamics analysis

Published:2019-10-31 Issue:15 Volume:38 Page:4432-4448
ISSN:0739-1102
Container-title:Journal of Biomolecular Structure and Dynamics
language:en
Short-container-title:Journal of Biomolecular Structure and Dynamics

Author:

Ma Yang-Chun¹,Yang Bing²,Wang Xin³,Zhou Liang¹,Li Wei-Ya¹,Liu Wen-Shan¹,Lu Xin-Hua⁴,Zheng Zhi-Hui⁴,Ma Ying¹,Wang Run-Ling¹

Affiliation:

1. Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics (Theranostics), School of Pharmacy, Tianjin Medical University, Tianjin, China;

2. Department of Cell Biology, School of Basic Medical Science, Tianjin Medical University, Tianjin, China;

3. Tasly Pharmaceutical Group Co., Ltd., Tianjin, China;

4. New Drug Research and Development Center of North China Pharmaceutical Group Corporation, National Microbial Medicine Engineering and Research Center, Hebei Industry Microbial Metabolic Engineering & Technology Research Center, Key Laboratory for New Drug Screening Technology of Shijiazhuang City, Shijiazhuang, Hebei, China

Publisher

Informa UK Limited

Subject

Molecular Biology,General Medicine,Structural Biology

Link

https://www.tandfonline.com/doi/pdf/10.1080/07391102.2019.1682050

Reference50 articles.

1. Advances in autism genetics: on the threshold of a new neurobiology

2. Simplified Receptor Based Pharmacophore Approach to Retrieve Potent PTP-LAR Inhibitors Using Apoenzyme

3. Structural genomics of protein phosphatases

4. Functional significance of the LAR receptor protein tyrosine phosphatase family in development and diseases

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