Discovery of 8-prenylnaringenin from hop (Humulus lupulus L.) as a potent monoacylglycerol lipase inhibitor for treatments of neuroinflammation and Alzheimer's disease-Reference-Cited by-同舟云学术

Discovery of 8-prenylnaringenin from hop (Humulus lupulus L.) as a potent monoacylglycerol lipase inhibitor for treatments of neuroinflammation and Alzheimer's disease

Published:2021 Issue:49 Volume:11 Page:31062-31072
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Tung Min-Che¹,Fung Kit-Man²,Hsu Hsin-Mie³,Tseng Tien-Sheng³^ORCID

Affiliation:

1. Division of Urology, Department of Surgery, Tungs' Taichung MetroHarbor Hospital, Taichung 435, Taiwan

2. Institute of Biological Chemistry, Academia Sinica, Taipei 115, Taiwan

3. Institute of Molecular Biology, National Chung Hsing University, Taichung, Taiwan

Abstract

Discovery of natural product inhibitors against human monoacylglycerol lipase by pharmacophore-based drug screening, LibDock molecular docking and in vitro biochemical examinations.

Funder

Ministry of Science and Technology, Taiwan

Tungs' Taichung MetroHarbor Hospital

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/RA/D1RA05311F

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