An in-silico investigation based on molecular simulations of novel and potential brain-penetrant GluN2B NMDA receptor antagonists as anti-stroke therapeutic agents-Reference-Cited by-同舟云学术

An in-silico investigation based on molecular simulations of novel and potential brain-penetrant GluN2B NMDA receptor antagonists as anti-stroke therapeutic agents

Published:2023-07-10 Issue: Volume: Page:1-15
ISSN:0739-1102
Container-title:Journal of Biomolecular Structure and Dynamics
language:en
Short-container-title:Journal of Biomolecular Structure and Dynamics

Author:

El fadili Mohamed¹^ORCID,Er-rajy Mohammed¹,Ali Eltayb Wafa²,Kara Mohammed³,Imtara Hamada⁴,Zarougui Sara¹,Al-Hoshani Nawal⁵,Hamadi Abdullah⁶,Elhallaoui Menana¹

Affiliation:

1. LIMAS Laboratory, Faculty of Sciences Dhar El Mehraz, Sidi Mohammed Ben Abdellah University, Fez, Morocco

2. Biotechnology Department, Faculty of Sciences and Technology, Shendi University, Shendi, Sudan

3. Laboratory of Biotechnology, Conservation and Valorisation of Naturals Resources, Faculty of Sciences Dhar El Mehraz, Sidi Mohamed Ben Abdellah University, Fez, Morocco

4. Faculty of Arts and Sciences, Arab American University Palestine, Jenin, Palestine

5. Department of Biology, College of Science, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia

6. Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, University of Tabuk, Tabuk, Saudi Arabia

Funder

Abdulrahman University Researchers

Publisher

Informa UK Limited

Subject

Molecular Biology,General Medicine,Structural Biology

Link

https://www.tandfonline.com/doi/pdf/10.1080/07391102.2023.2232024

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5. Bank, R. P. D. (n.d.). RCSB PDB – 3QEL: Crystal structure of amino terminal domains of the NMDA receptor subunit GluN1 and GluN2B in complex with ifenprodil. Retrieved June 13, 2023, from https://www.rcsb.org/structure/3QEL

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