In vitro metabolism of alectinib, a novel potent ALK inhibitor, in human: contribution of CYP3A enzymes
Author:
Affiliation:
1. Chugai Pharmaceutical Co. Ltd., Gotemba, Japan,
2. Non-Clinical Drug Safety, F. Hoffmann-La Roche Ltd., Basel, Switzerland,
3. Roche Innovation Center, New York, NY, USA
Publisher
Informa UK Limited
Subject
Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine
Link
https://www.tandfonline.com/doi/pdf/10.1080/00498254.2017.1344910
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4. Identification of Novel Isoforms of the EML4-ALK Transforming Gene in Non–Small Cell Lung Cancer
5. Isolated central nervous system progression on Crizotinib
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