Effects of drug-drug interactions and CYP3A4 variants on alectinib metabolism
Author:
Publisher
Springer Science and Business Media LLC
Subject
Health, Toxicology and Mutagenesis,Toxicology,General Medicine
Link
https://link.springer.com/content/pdf/10.1007/s00204-023-03524-1.pdf
Reference34 articles.
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2. Androutsopoulos VP, Tsatsakis AM, Spandidos DA (2009b) Cytochrome P450 CYP1A1: wider roles in cancer progression and prevention. BMC Cancer 9:187. https://doi.org/10.1186/1471-2407-9-187
3. Androutsopoulos VP, Papakyriakou A, Vourloumis D, Tsatsakis AM, Spandidos DA (2010) Dietary flavonoids in cancer therapy and prevention: substrates and inhibitors of cytochrome P450 CYP1 enzymes. Pharmacol Ther 126(1):9–20. https://doi.org/10.1016/j.pharmthera.2010.01.009
4. Calvo E, Lee J-S, Kim S-W et al (2019) Modulation of fexofenadine pharmacokinetics by osimertinib in patients with advanced EGFR-mutated non-small cell lung cancer. J Clin Pharmacol 59(8):1099–1109. https://doi.org/10.1002/jcph.1403
5. Cleary Y, Gertz M, Morcos PN et al (2018) Model-based assessments of CYP-mediated drug-drug interaction risk of alectinib: physiologically based pharmacokinetic modeling supported clinical development. Clin Pharmacol Ther 104(3):505–514. https://doi.org/10.1002/cpt.956
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