Use of physiologically based pharmacokinetic modeling for assessment of drug–drug interactions
Author:
Affiliation:
1. F. Hoffmann-La Roche Ltd, Non-ClinicalSafety, Pharmaceuticals Division, Bau 70/130, CH-4070 Basel, Switzerland
2. F. Hoffmann-La Roche Ltd, Non-ClinicalSafety, Pharmaceuticals Division, Bau 70/130, CH-4070 Basel, Switzerland.
Abstract
Publisher
Future Science Ltd
Subject
Drug Discovery,Pharmacology,Molecular Medicine
Link
http://www.future-science.com/doi/pdf/10.4155/fmc.12.13
Reference66 articles.
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5. Sorivudine and 5‐fluorouracil; a clinically significant drug‐drug interaction due to inhibition of dihydropyrimidine dehydrogenase
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