Small molecule correctors of F508del-CFTR discovered by structure-based virtual screening-Reference-Cited by-同舟云学术

Small molecule correctors of F508del-CFTR discovered by structure-based virtual screening

Published:2010-10-26 Issue:12 Volume:24 Page:971-991
ISSN:0920-654X
Container-title:Journal of Computer-Aided Molecular Design
language:en
Short-container-title:J Comput Aided Mol Des

Author:

Kalid Ori,Mense Martin,Fischman Sharon,Shitrit Alina,Bihler Hermann,Ben-Zeev Efrat,Schutz Nili,Pedemonte Nicoletta,Thomas Philip J.,Bridges Robert J.,Wetmore Diana R.,Marantz Yael,Senderowitz Hanoch

Publisher

Springer Science and Business Media LLC

Subject

Physical and Theoretical Chemistry,Computer Science Applications,Drug Discovery

Link

http://link.springer.com/content/pdf/10.1007/s10822-010-9390-0.pdf

Reference66 articles.

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2. Riordan JR (2008) Cftr function and prospects for therapy. Annu Rev Biochem 77:701–726

3. Davis PB (2006) Cystic fibrosis since 1938. Am J Respir Crit Care Med 173(5):475–482

4. Du K, Lukacs GL (2009) Cooperative assembly and misfolding of cftr domains in vivo. Mol Biol Cell 20(7):1903–1915

5. Du K, Sharma M, Lukacs GL (2005) The deltaf508 cystic fibrosis mutation impairs domain-domain interactions and arrests post-translational folding of cftr. Nat Struct Mol Biol 12(1):17–25

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