Abstract
AbstractMicroalgae are considered promising sustainable sources of natural bioactive compounds to be used in biotechnological sectors. In recent years, attention is increasingly given to the search of microalgae-derived compounds with antioxidant and anti-inflammatory properties for nutraceutical or pharmacological issues. In this context, attention is usually focused on the composition and bioactivity of algae or their extracts, while less interest is driven to their biological features, for example, those related to morphology and cultivation conditions. In addition, specific studies on the antioxidant and anti-inflammatory properties of microalgae mainly concern Chlorella or Spirulina. The present work was focused on the characterization of the Chlorophyta Neochloris oleoabundans under two combinations of cultivation modes: autotrophy and glucose-induced mixotrophy, each followed by starvation. Biomass for morphological and biochemical characterization, as well as for extract preparation, was harvested at the end of each cultivation phase. Analyses indicated a different content of the most important classes of bioactive compounds with antioxidant/anti-inflammatory properties (lipids, exo-polysaccharides, pigments, total phenolics, and proteins). In particular, the most promising condition able to prompt the production of antioxidant algal biomass with anti-inflammatory properties was the mixotrophic one. Under mixotrophy, beside an elevated algal biomass production, a strong photosynthetic metabolism with high appression of thylakoid membranes and characteristics of high photo-protection from oxidative damage was observed and linked to the overproduction of exo-polysaccharides and lipids rather than pigments. Overall, mixotrophy appears a good choice to produce natural bioactive extracts, potentially well tolerated by human metabolism and environmentally sustainable.
Funder
University of Ferrara
Università degli Studi di Ferrara
Publisher
Springer Science and Business Media LLC
Reference118 articles.
1. Abreu AP, Morais RC, Teixeira JA, Nunes J (2022) A comparison between microalgal autotrophic growth and metabolite accumulation with heterotrophic, mixotrophic and photoheterotrophic cultivation modes. Renew Sust Energ Rev 159:112247. https://doi.org/10.1016/j.rser.2022.112247
2. Abu-Hajar HA, Riefler RG, Stuart BJ (2017) Cultivation of the microalga Neochloris oleoabundans for biofuels production and other industrial applications (a review). Appl Biochem Microbiol 53:640–653. https://doi.org/10.1134/S0003683817060096
3. Al Jabri H, Taleb A, Touchard R, Saadaoui I, Goez V, Pruvost J (2021) Cultivating microalgae in desert conditions: evaluation of the effect of light-temperature summer conditions on the growth and metabolism of Nannochloropsis QU130. Appl Sci 11:3799. https://doi.org/10.3390/app11093799
4. Almendinger M, Saalfrank F, Rohn S, Kurth E, Springer M, Pleissner D (2021) Characterization of selected microalgae and cyanobacteria as sources of compounds with antioxidant capacity. Algal Res 53:102168. https://doi.org/10.1016/j.algal.2020.102168
5. Amaro HM, Guedes AC, Malcata FX (2011) Antimicrobial activities of microalgae: an invited review. In Science against microbial pathogens: communicating current research and technological advances. Mendez-Vilas A Ed. Formatex Microbiology book series, pp 1272–1280
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