Dysfunctional γ-Secretase in Familial Alzheimer’s Disease
Author:
Funder
National Institute on Aging
Publisher
Springer Science and Business Media LLC
Subject
Cellular and Molecular Neuroscience,General Medicine,Biochemistry
Link
http://link.springer.com/article/10.1007/s11064-018-2511-1/fulltext.html
Reference50 articles.
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3. Bursavich MG, Harrison BA, Blain JF (2016) Gamma secretase modulators: new Alzheimer’s drugs on the horizon? J Med Chem 59:7389–7409
4. Cai XD, Golde TE, Younkin SG (1993) Release of excess amyloid beta protein from a mutant amyloid beta protein precursor. Science 259:514–516
5. Chavez-Gutierrez L, Bammens L, Benilova I, Vandersteen A, Benurwar M, Borgers M, Lismont S, Zhou L, Van Cleynenbreugel S, Esselmann H, Wiltfang J, Serneels L, Karran E, Gijsen H, Schymkowitz J, Rousseau F, Broersen K, De Strooper B (2012) The mechanism of gamma-secretase dysfunction in familial Alzheimer disease. EMBO J 31:2261–2274
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