Discovering Echinococcus granulosus thioredoxin glutathione reductase inhibitors through site-specific dynamic combinatorial chemistry

Author:

Saiz Cecilia,Castillo Valerie,Fontán Pablo,Bonilla Mariana,Salinas Gustavo,Rodríguez-Haralambides Alejandra,Mahler S. Graciela

Publisher

Springer Science and Business Media LLC

Subject

Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Drug Discovery,Molecular Biology,General Medicine,Information Systems,Catalysis

Reference28 articles.

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3. Folkers G, Jahnke W, Erlanson DA, Mannhold R, Kubinyi H (2006) The concept of fragment-based drug discovery. In: Jahnke W, Erlanson DA (eds) Fragment-based approaches in drug discovery. Wiley-VCH Verlag GmbH and Co. KGaA, Weinheim, pp 1–10. doi: 10.1002/3527608761.ch1

4. Murray CW, Verdonk ML, Rees DC (2012) Experiences in fragment-based drug discovery. Trends Pharmacol Sci 33:224–232. doi: 10.1016/j.tips.2012.02.006

5. Hajduk PJ, Greer J (2007) A decade of fragment-based drug design: strategic advances and lessons learned. Nat Rev Drug Discov 6:211–219. doi: 10.1038/nrd2220

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