Synthesis, molecular docking, analgesic, anti-inflammatory, and ulcerogenic evaluation of thiophene-pyrazole candidates as COX, 5-LOX, and TNF-α inhibitors-Reference-Cited by-同舟云学术

Synthesis, molecular docking, analgesic, anti-inflammatory, and ulcerogenic evaluation of thiophene-pyrazole candidates as COX, 5-LOX, and TNF-α inhibitors

Published:2023-11-20 Issue: Volume: Page:
ISSN:0925-4692
Container-title:Inflammopharmacology
language:en
Short-container-title:Inflammopharmacol

Author:

Khadri M. J. Nagesh,Ramu Ramith,Simha N. Akshaya,Khanum Shaukath Ara^ORCID

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology,Immunology

Link

https://link.springer.com/content/pdf/10.1007/s10787-023-01364-0.pdf

Reference50 articles.

1. Abd El-Karim SS et al (2021) Design, synthesis and molecular docking of new pyrazole-thiazolidinones as potent anti-inflammatory and analgesic agents with TNF-α inhibitory activity. Bioorg Chem 111(January):104827. https://doi.org/10.1016/j.bioorg.2021.104827

2. Abdelgawad MA et al (2018) Design, synthesis, analgesic, anti-inflammatory activity of novel pyrazolones possessing aminosulfonyl pharmacophore as inhibitors of COX-2/5-LOX enzymes: Histopathological and docking studies. Bioorgan Chem 78:103–114. https://doi.org/10.1016/j.bioorg.2018.03.011

3. Ahmed AHH et al (2022) Design, synthesis, and molecular docking of novel pyrazole-chalcone analogs of lonazolac as 5-LOX, iNOS and tubulin polymerization inhibitors with potential anticancer and anti-inflammatory activities. Bioorganic Chemistry 129:106171. https://doi.org/10.1016/j.bioorg.2022.106171

4. Alanazi AM et al (2015) Structure-based design of phthalimide derivatives as potential cyclooxygenase-2 (COX-2) inhibitors: anti-inflammatory and analgesic activities. Eur J Med Chem 92:115–123. https://doi.org/10.1016/j.ejmech.2014.12.039

5. Alfi AA et al (2022) Molecular modeling and docking studies of new antioxidant pyrazole-thiazole hybrids. J Mol Struct 1267:133582. https://doi.org/10.1016/j.molstruc.2022.133582

Cited by 2 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Exploring Thiophene Derivatives: Synthesis Strategies and Biological Significance;Medicinal Chemistry;2024-08-08

2. Sustainable click reactions: Use of greener reaction media in the synthesis of 1,2,3-triazoles;Tetrahedron;2024-05