The in vitro pharmacology of the peripherally restricted opioid receptor antagonists, alvimopan, ADL 08-0011 and methylnaltrexone-Reference-Cited by-同舟云学术

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The in vitro pharmacology of the peripherally restricted opioid receptor antagonists, alvimopan, ADL 08-0011 and methylnaltrexone

Published:2007-03-06 Issue:3 Volume:375 Page:205-220
ISSN:0028-1298
Container-title:Naunyn-Schmiedeberg's Archives of Pharmacology
language:en
Short-container-title:Naunyn-Schmied Arch Pharmacol

Author:

Beattie D. T.,Cheruvu M.,Mai N.,O’Keefe M.,Johnson-Rabidoux S.,Peterson C.,Kaufman E.,Vickery R.

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology,General Medicine

Link

http://link.springer.com/content/pdf/10.1007/s00210-007-0146-x.pdf

Reference54 articles.

1. Ammer H, Schulz R (1993) Alteration in the expression of G-proteins and regulation of adenylate cyclase in human neuroblastoma SH-SY5Y cells chronically exposed to low-efficacy μ-opioids. Biochem J 295:263–271

2. Arunlakshana O, Schild HO (1959) Some quantitative uses of drug antagonists. Br J Pharmacol 14:48–58

3. Bailey CP, Couch D, Johnson E, Griffiths K, Kelly E, Henderson G (2003) μ-Opioid receptor desensitization in mature rat neurons: lack of interaction between DAMGO and morphine. J Neurosci 23:10515–10520

4. Becker JAJ, Wallace A, Garzon A, Ingallinella P, Bianchi E, Cortese R, Simonin F, Kieffer BL, Pessi A (1999) Ligands for κ-opioid and ORL1 receptors identified from a conformationally constrained peptide combinatorial library. J Biol Chem 274:27513–27522

5. Bennett MA, Murray TF, Aldrich JV (2005) Structure-activity relationships of arodyn, a novel acetylated kappa opioid receptor antagonist. J Pept Res 65:322–332

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4. Methylnaltrexone crosses the blood-brain barrier and attenuates centrally-mediated behavioral effects of morphine and oxycodone in mice;Neuropharmacology;2021-03

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