Qualitative analysis of zolpidem and its metabolites M-1 to M-4 in human blood and urine using liquid chromatography–tandem mass spectrometry
Author:
Funder
Japan Society for the Promotion of Science
Publisher
Springer Science and Business Media LLC
Subject
Biochemistry, medical,Toxicology,Pathology and Forensic Medicine
Link
https://link.springer.com/content/pdf/10.1007/s11419-020-00551-w.pdf
Reference11 articles.
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3. Ascalone V, Flaminio L, Guinebault P, Thenot JP, Morselli PL (1992) Determination of zolpidem, a new sleep-inducing agent, and its metabolites in biological fluids: pharmacokinetics, drug metabolism and investigations in humans. J Chromatogr 581:237–250
4. Mingozzi M, Manzoni L, Arosio D, Dal Corso A, Manzotti M, Innamorati F, Pignataro L, Lecis D, Delia D, Seneci P, Gennari C (2014) Synthesis and biological evaluation of dual action cyclo-RGD/SMAC mimetic conjugates targeting α(v)β(3)/α(v)β(5) integrins and IAP proteins. Org Biomol Chem 12:3288–3302
5. Chernyak N, Gevorgyan V (2010) General and efficient copper-catalyzed three-component coupling reaction towards imidazoheterocycles: one-pot synthesis of alpidem and zolpidem. Angew Chem Int Ed Engl 49:2743–2746
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