Greener and whiter analytical method development and validation for determining the presence of zolpidem tartrate infused in apple juice using RP-HPLC via magnetic solid-phase extraction followed by LC-MS confirmatory analysis

Author:

Sundara Moorthy Revathy1ORCID,Swetha G.1,Rondla Rohini2,Hu Anren3,Vallakeerthi Narmada4,Reddy P. Muralidhar1ORCID

Affiliation:

1. Department of Chemistry, University College of Science, Osmania University, Tarnaka, Hyderabad, Telangana 500007, India

2. Department of Chemistry (H & S), Vidya Jyothi Institute of Technology, Aziz Nagar Gate, Hyderabad, Telangana 500075, India

3. Department of Laboratory Medicine and Biotechnology, Tzu Chi University, Haulien 97004, Taiwan

4. Department of Pharmacy, University College of Technology, Osmania University, Hyderabad 500007, Telangana, India

Abstract

The research work entails a newly developed RP-HPLC method, aimedat analyzing the modern date rape drug, zolpidem tartrate (ZT), infused in apple juice matrix.

Funder

Tzu Chi University

Ministry of Science and Technology, Taiwan

Osmania University

Publisher

Royal Society of Chemistry (RSC)

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