Increase in the sensitivity to PLX4720 through inhibition of transcription factor EB-dependent autophagy in BRAF inhibitor-resistant cells
Author:
Funder
incheon national university
Publisher
Springer Science and Business Media LLC
Subject
Health, Toxicology and Mutagenesis,Toxicology
Link
https://link.springer.com/content/pdf/10.1007/s43188-021-00109-x.pdf
Reference40 articles.
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2. Menzies AM, Long GV (2014) Dabrafenib and trametinib, alone and in combination for BRAF-mutant metastatic melanoma. Clin Cancer Res 20:2035–2043. https://doi.org/10.1158/1078-0432.CCR-13-2054
3. Bollag G, Tsai J, Zhang J, Zhang C, Ibrahim P, Nolop K et al (2012) Vemurafenib: the first drug approved for BRAF-mutant cancer. Nat Rev Drug Discovery 11:873–886. https://doi.org/10.1038/nrd3847
4. Luebker SA, Koepsell SA (2019) Diverse mechanisms of BRAF inhibitor resistance in melanoma identified in clinical and preclinical studies. Front Oncol 9:268. https://doi.org/10.3389/fonc.2019.00268
5. Hatzivassiliou G, Song K, Yen I, Brandhuber BJ, Anderson DJ, Alvarado R et al (2010) RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth. Nature 464:431–435. https://doi.org/10.1038/nature08833
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