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Decitabine improves progression-free survival in older high-risk MDS patients with multiple autosomal monosomies: results of a subgroup analysis of the randomized phase III study 06011 of the EORTC Leukemia Cooperative Group and German MDS Study Group

  • Published:2015-11-23 Issue:2 Volume:95 Page:191-199
  • ISSN:0939-5555
  • Container-title:Annals of Hematology
  • language:en
  • Short-container-title:Ann Hematol

Author:

Lübbert Michael, ,Suciu Stefan,Hagemeijer Anne,Rüter Björn,Platzbecker Uwe,Giagounidis Aristoteles,Selleslag Dominik,Labar Boris,Germing Ulrich,Salih Helmut R.,Muus Petra,Pflüger Karl-Heinz,Schaefer Hans-Eckart,Bogatyreva Lioudmila,Aul Carlo,de Witte Theo,Ganser Arnold,Becker Heiko,Huls Gerwin,van der Helm Lieke,Vellenga Edo,Baron Frédéric,Marie Jean-Pierre,Wijermans Pierre W.

Funder

EORTC Charitable Trust

MGI Pharma

Janssen Research and Development

Deutsche Forschungsgemeinschaft (DE)

Publisher

Springer Science and Business Media LLC

Subject

Hematology,General Medicine

Reference31 articles.

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2. Greenberg PL, Tuechler H, Schanz J, Sanz G, Garcia-Manero G, Sole F, Bennett JM, Bowen D, Fenaux P, Dreyfus F, Kantarjian H, Kuendgen A, Levis A, Malcovati L, Cazzola M, Cermak J, Fonatsch C, Le Beau MM, Slovak ML, Krieger O, Lubbert M, Maciejewski J, Magalhaes SMM, Miyazaki Y, Pfeilstöcker M, Sekeres M, Sperr WR, Stauder R, Tauro S, Valent P, Vallespi T, van de Loosdrecht AA, Germing U, Haase D (2012) Revised international prognostic scoring system for myelodysplastic syndromes. Blood 120(12):2454–2465. doi: 10.1182/blood-2012-03-420489

3. Haase D, Germing U, Schanz J, Pfeilstöcker M, Nösslinger T, Hildebrandt B, Kündgen A, Lübbert M, Kunzmann R, Giagounidis AAN, Aul C, Trümper L, Krieger O, Stauder R, Müller TH, Wimazal F, Valent P, Fonatsch C, Steidl C (2007) New insights into the prognostic impact of the karyotype in MDS and correlation with subtypes: evidence from a core dataset of 2124 patients. Blood 110(13):4385–4395. doi: 10.1182/blood-2007-03-082404

4. Kayser S, Zucknick M, Döhner K, Krauter J, Köhne CH, Horst HA, Held G, von Lilienfeld-Toal M, Wilhelm S, Rummel M, Germing U, Götze K, Nachbaur D, Schlegelberger B, Göhring G, Späth D, Morlok C, Teleanu V, Ganser A, Döhner H, Schlenk RF (2011) Monosomal karyotype in adult acute myeloid leukemia: prognostic impact and outcome after different treatment strategies. Blood 119(2):551–558. doi: 10.1182/blood-2011-07-367508

5. Döhner H, Estey EH, Amadori S, Appelbaum FR, Büchner T, Burnett AK, Dombret H, Fenaux P, Grimwade D, Larson RA, Lo-Coco F, Naoe T, Niederwieser D, Ossenkoppele GJ, Sanz MA, Sierra J, Tallman MS, Löwenberg B, Bloomfield CD (2009) Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European leukemiaNet. Blood 115(3):453–474. doi: 10.1182/blood-2009-07-235358
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