Large-scale production of ursodeoxycholic acid from chenodeoxycholic acid by engineering 7α- and 7β-hydroxysteroid dehydrogenase
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Medicine,Bioengineering,Biotechnology
Link
http://link.springer.com/content/pdf/10.1007/s00449-019-02151-4.pdf
Reference23 articles.
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2. Fieser LF, Herz JE, Klohs MW, Romero MA, Utne T (1952) Cathylation (carbethoxylation) of steroid alcohols. J Am Chem Soc 74:3309–3313
3. Hu XZ, Liu AJ (2013) Method for producing ursodesoxycholic acid by using chenodeoxycholic acid as raw material. Chinese Patent CN102911235
4. Tian H, Zhao HB, Cao XJ (2013) Catalytic transfer hydrogenation of 7-ketolithocholic acid to ursodeoxycholic acid with Raney nickel. J Ind Eng Chem 19:606–613
5. Yuan XX, Ma XL, Cao XJ (2014) Preparation of ursodeoxycholic acid by direct electro-reduction of 7-ketolithocholic acid. Korean J Chem Eng 31:1276–1280
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