Ursodeoxycholic Acid (UDCA) Can Inhibit Deoxycholic Acid (DCA)-induced Apoptosis via Modulation of EGFR/Raf-1/ERK Signaling in Human Colon Cancer Cells
Author:
Affiliation:
1. Arizona Cancer Center, Department of Radiation Oncology, University of Arizona, Tucson, AZ 85724
Publisher
Oxford University Press (OUP)
Subject
Nutrition and Dietetics,Medicine (miscellaneous)
Link
http://academic.oup.com/jn/article-pdf/134/2/483/24010016/z4w00204000483.pdf
Reference17 articles.
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2. Different bile acids exhibit distinct biological effects: the tumor promoter deoxycholic acid induces apoptosis and the chemopreventive agent ursodeoxycholic acid inhibits cell proliferation;Martinez;Nutr. Cancer,1998
3. Physicochemical properties of bile acids and their relationship to biological properties: an overview of the problem;Hofmann;J. Lipid Res.,1984
4. Effects of deoxycholate on human colon cancer cells: apoptosis or proliferation;Milovic;Eur. J. Clin. Invest.,2002
5. A novel role for ursodeoxycholic acid in inhibiting apoptosis by modulating mitochondrial membrane perturbation;Rodrigues;J. Clin. Invest.,1998
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