High Enantioselective and Large-Scale Production of Ursodeoxycholic Acid by Combination of Pd- and Hydroxysteroid Dehydrogenase-Catalyzed Hydrogenation-Reference-Cited by-同舟云学术

High Enantioselective and Large-Scale Production of Ursodeoxycholic Acid by Combination of Pd- and Hydroxysteroid Dehydrogenase-Catalyzed Hydrogenation

Published:2024-03-19 Issue:4 Volume:28 Page:1260-1268
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Zeng Chunling¹²,Liu Xirong¹²,Sun Chao²,Xu Xinhua¹²^ORCID,Peng Lifen¹²

Affiliation:

1. State Key Laboratory of Chemo/Biosensing and Chemometrics, Advanced Catalytic Engineering Research Center of the Ministry of Education, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, P. R. China

2. Engineering Research Center of Phytosterol Microbial Transformation and Synthetic Biology of Hunan Province, Hunan Norchem Pharmaceutical Company, Ltd., Changsha 410000, P. R. China

Funder

Natural Science Foundation of Hunan Province

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.4c00057

Reference40 articles.

1. Ursodeoxycholic acid in cholestatic liver disease: Mechanisms of action and therapeutic use revisited

2. Ursodeoxycholic acid: Mechanism of action and novel clinical applications

3. Ursodeoxycholic acid is associated with a reduction in SARS‐CoV‐2 infection and reduced severity of COVID‐19 in patients with cirrhosis

4. Enzymatic routes for the synthesis of ursodeoxycholic acid

5. Latest development in the synthesis of ursodeoxycholic acid (UDCA): a critical review

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