A convenient synthesis, reactions and biological evaluation of novel pyrazolo[3,4-b]selenolo[3,2-e]pyrazine heterocycles as potential anticancer and antimicrobial agents

Author:

Zaki Remon M.ORCID,Abdul-Malik Mokhtar A.,Saber Saber H.,Radwan Shaban M.,El-Dean Adel M. Kamal

Publisher

Springer Science and Business Media LLC

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics

Reference35 articles.

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2. Ahmad M, Hameed S, Tahir MN, Israr M, Anwar M, Shah MA, et al. Synthesis, characterization and biological evaluation of some 5- methyl pyrazine carbohydrazide based hydrazones. Pak J Pharm Sci. 2016;29:811–7.

3. Farghaly A, Esmail S, Abdel-Zaher A, Abdel-Hafez A, El-Kashef H. Synthesis and anticonvulsant activity of some new pyrazolo[3,4-b]pyrazines and related heterocycles. Bioorg Med Chem. 2014;22:2166–75. https://doi.org/10.1016/j.bmc.2014.02.019.

4. El-Kashef HS, El-Emary TI, Gasquet M, Timon-David P, Maldonado J, Vanelle P. New pyrazolo[3,4-b]pyrazines: synthesis and biological activity. Pharmazie. 2000;55:572–6.

5. Imaizumi K, Sado T. Bone metabolism improvers containing pyrazolopyrazine, Jpn. Kokai Tokkyo Koho JP 06 80 570 [9480 5701 (Cl. AGlK31/495). Chem Abstr. 1994;121:91797w.

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