Novel Curcumin Monocarbonyl Analogue-Dithiocarbamate hybrid molecules target human DNA ligase I and show improved activity against colon cancer
Author:
Funder
CSIR-CDRI
Publisher
Springer Science and Business Media LLC
Subject
Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics
Link
https://link.springer.com/content/pdf/10.1007/s00044-022-02983-y.pdf
Reference38 articles.
1. Singh DK, Hussain MK, Krishna S, Deshmukh AL, Shameem M, Maurya P, et al. Identification of a novel human DNA ligase i inhibitor that promotes cellular apoptosis in DLD-1 cells: An: in silico and in vitro mechanistic study. RSC Adv. 2016;6:94574–87. https://doi.org/10.1039/c6ra22364h
2. Curtin NJ. DNA repair dysregulation from cancer driver to therapeutic target. Nat Rev Cancer. 2012;12:801–17. https://doi.org/10.1038/nrc3399
3. Hoeijmakers JHJ. Genome maintenance mechanisms for preventing cancer. Nature. 2001;411:366–74. https://doi.org/10.1038/35077232
4. Puigvert JC, Sanjiv K, Helleday T. Targeting DNA repair, DNA metabolism and replication stress as anti-cancer strategies. FEBS J. 2016;283:232–45. https://doi.org/10.1111/febs.13574
5. Deshmukh AL, Kumar C, Singh DK, Maurya P, Banerjee D. Dynamics of replication proteins during lagging strand synthesis: A crossroads for genomic instability and cancer. DNA Repair. 2016;42:72–81. https://doi.org/10.1016/j.dnarep.2016.04.010
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1. Synthesis of thiazolo[3,2-a]pyrimidine molecules, in vitro cytotoxic evaluation and molecular docking studies;Journal of the Iranian Chemical Society;2023-03-04
2. Correction: Novel Curcumin Monocarbonyl Analogue-Dithiocarbamate hybrid molecules target human DNA ligase I and show improved activity against colon cancer;Medicinal Chemistry Research;2022-12-24
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