IFN-α induces a preferential long-lasting expression of MHC class I in human pancreatic beta cells-Reference-Cited by-同舟云学术

IFN-α induces a preferential long-lasting expression of MHC class I in human pancreatic beta cells

Published:2018-01-05 Issue:3 Volume:61 Page:636-640
ISSN:0012-186X
Container-title:Diabetologia
language:en
Short-container-title:Diabetologia

Author:

Coomans de Brachène Alexandra^ORCID,Dos Santos Reinaldo S.,Marroqui Laura,Colli Maikel L.,Marselli Lorella,Mirmira Raghavendra G.,Marchetti Piero,Eizirik Decio L.

Publisher

Springer Science and Business Media LLC

Subject

Endocrinology, Diabetes and Metabolism,Internal Medicine

Link

http://link.springer.com/article/10.1007/s00125-017-4536-4/fulltext.html

Reference12 articles.

1. Richardson SJ, Rodriguez-Calvo T, Gerling IC et al (2016) Islet cell hyperexpression of HLA class I antigens: a defining feature in type 1 diabetes. Diabetologia 59:2448–2458

2. Foulis AK, Farquharson MA, Meager A (1987) Immunoreactive alpha-interferon in insulin-secreting beta cells in type 1 diabetes mellitus. Lancet 2:1423–1427

3. Bending D, Zaccone P, Cooke A (2012) Inflammation and type 1 diabetes. Int Immunol 24:339–346

4. Marroqui L, Dos Santos RS, Op de Beeck A et al (2017) Interferon-alpha mediates human beta cell HLA class I overexpression, endoplasmic reticulum stress and apoptosis, three hallmarks of early human type 1 diabetes. Diabetologia 60:656–667

5. Marroqui L, Dos Santos RS, Floyel T et al (2015) TYK2, a candidate gene for type 1 diabetes, modulates apoptosis and the innate immune response in human pancreatic beta-cells. Diabetes 64:3808–3817

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